Summary

The Glomerular Filtration Rate Estimate by CKD-EPI Equation method calculates its output using form inputs and data retrieved from the Demographics form. See Merk Manuals for details about the equation itself as well as an online calculator.

Note this method is currently based on the 2009 CKD-EPI calculation. This page will be updated once updated method based on 2021 version is created.

Formal Expression

var isBlackItemName = 'DM Race - Black Or African American';
var demographicsEventName = 'Screening';
var demographicsFormName = 'Demographics';
var serumCreatinine = findFirstItemByName(formJson,'Serum Creatinine').value;

var demographics = findFormData(demographicsEventName, demographicsFormName);
var isBlack = findFirstItemByName(demographics[0], isBlackItemName).value;
var sex = findFirstItemByName(demographics[0], 'Sex').value;
var age = findFirstItemByName(demographics[0], 'Age').value;

var sexFactor = 1.018; 
var alpha = -0.329; 
var kappa = 0.7;
var raceFactor = (isBlack == 'true') ? 1.159 : 1;
if (sex == 'MALE') {
  sexFactor = 1; 
  alpha = -0.411; 
  kappa = 0.9;
}

// GFR = 141 * min(Serum_creatinine/kappa, 1)alpha * max(Serum_creatinine/kappa, 1) -1.209 * 0.993Age * Sex * Race
var gfr = 141 * Math.pow(Math.min(serumCreatinine/kappa, 1),alpha) * Math.pow(Math.max(serumCreatinine/kappa, 1),-1.209) * Math.pow(0.993, age) * sexFactor * raceFactor ;

return parseFloat(toFixed(gfr, 2));

function toFixed(num, fixed) {  // truncate after fixed # of decimals, no rounding
    var re = new RegExp('^-?\\d+(?:\.\\d{0,' + (fixed || -1) + '})?');
    return num.toString().match(re)[0];
}