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You may amend the Name of the ClinSpark environment in the Organization Basics section. This is the Name that will appear in the upper left hand side of the application screen.
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Organization Basics > Timezone
You may define the system-wide Timezone in this area. This can be adjusted on a Site by Site per environment basis.
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Organization Basics > Org URL
The Org URL setting that you can see in the screenshot is only accessible to the Foundry Health is made visible to users, but can only be modified by IQVIA superadmin users.